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CM-Polysucrose

Carboxymethyl-Polysucroses (CM-Polysucrose) are white, odourless and tasteless powders which are freely soluble in water or electrolyte solutions.

CM-Polysucrose consists of Polysucrose (renamed from Ficoll™) substituted with carboxymethyl groups imparting a polyanionic character to the product. The carboxymethyl content corresponds to about 1 CM group for every 5 glycose units. 

If you need larger quantities please contact us for a bulk quotation.

Ficoll™ is a trademark owned by GE Healthcare.

References

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  1. Li, B. et al. Functionalized polymer microbubbles as new molecular ultrasound contrast agent to target P-selectin in thrombus. Biomaterials 194, 139–150 (2019).
  2. Hwang, H. et al. MESIA: Magnetic force-assisted electrochemical sandwich immunoassays for quantification of prostate-specific antigen in human serum. Analytica Chimica Acta 1061, 92–100 (2019).
  3. Juenet, M. et al. Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin. Biomaterials 156, 204–216 (2018).
  4. Nultsch, K. & Germershaus, O. Silk fibroin degumming affects scaffold structure and release of macromolecular drugs. European Journal of Pharmaceutical Sciences 106, 254–261 (2017).
  5. Käsdorf, B. T. et al. Mucin-Inspired Lubrication on Hydrophobic Surfaces. Biomacromolecules 18, 2454–2462 (2017).
  6. Ficko, B. W., NDong, C., Giacometti, P., Griswold, K. E. & Diamond, S. G. A Feasibility Study of Nonlinear Spectroscopic Measurement of Magnetic Nanoparticles Targeted to Cancer Cells. IEEE Transactions on Biomedical Engineering 64, 972–979 (2017).
  7. Burke, M. et al. Regulation of Scaffold Cell Adhesion Using Artificial Membrane Binding Proteins. Macromolecular Bioscience 17, 1600523 (2017).
  8. Ndong, C. et al. Antibody-mediated targeting of iron oxide nanoparticles to the folate receptor alpha increases tumor cell association in vitro and in vivo. Int J Nanomedicine 10, 2595–2617 (2015).
  9. Terentyeva, T. G. et al. Bioactive flake–shell capsules: soft silica nanoparticles for efficient enzyme immobilization. J. Mater. Chem. B 1, 3248–3256 (2013).
  10. Asgeirsson, D., Venturoli, D., Rippe, B. & Rippe, C. Increased glomerular permeability to negatively charged Ficoll relative to neutral Ficoll in rats. American Journal of Physiology-Renal Physiology 291, F1083–F1089 (2006).
  11. Koltun, M., Nikolovski, J., Strong, K., Nikolic-Paterson, D. & Comper, W. D. Mechanism of hypoalbuminemia in rodents. American Journal of Physiology-Heart and Circulatory Physiology 288, H1604–H1610 (2005).
  12. Landauer, K. et al. Influence of Carboxymethyl Dextran and Ferric Citrate on the Adhesion of CHO Cells on Microcarriers. Biotechnology Progress 19, 21–29 (2003).
  13. Guimarães, M. A. M., Nikolovski, J., Pratt, L. M., Greive, K. & Comper, W. D. Anomalous fractional clearance of negatively charged Ficoll relative to uncharged Ficoll. American Journal of Physiology-Renal Physiology 285, F1118–F1124 (2003).

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Carboxymethyl-Polysucrose 70 (CMP70)

Carboxymethyl-Polysucrose 70 (CMP70)

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