CAS No. 9015-73-0
DEAE-substituents have been introduced into a range of dextran fractions. The chemical reaction introduces two types of substituents.
The predominant substituent is the single tertiary group (blue) but this reacts further in some cases to yield a "tandem" group (red) containing a quarternary amine as well as the tertiary amine. A titration curve reveals the proportions (Fig.2).
DEAE-dextrans are supplied as a white hygroscopic powder which are readily soluble in water and salt solutions. The powder is stable at room temperature for more than three years providing it is stored in well-sealed containers in the dark.
DEAE-dextrans are used in various areas:
- As adjuvant for vaccines
- In transfection techniques and viral infectivity
- For stabilisation of proteins (enzymes)
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