Polysucrose

Polysucrose

CAS Number: 26873-85-8

Polysucroses (renamed from Ficoll™) are formed by copolymerization of sucrose with epichlorohydrin. These molecules are highly branched, and the high content of hydroxyl groups leads to very good solubility in aqueous media. Polysucrose behaves as an ideal neutral sphere and displays excellent biocompatibility. It does not contain any ionized groups, so it is compatible under physiological conditions. However, it is more sensitive to acid than dextran, so care must be taken when working under acidic pH conditions.

Properties of the polysucroses include:

  • Readily soluble in water and electrolyte solution
  • Clear and stable solutions
  • No charged groups - neutral polymer
  • Excellent biocompatibility
  • Excellent stability - can be autoclaved
  • From renewable resources and is readily degraded in ecological systems

All batches are checked for molecular weight, degree of substitution and loss on drying. TdB Labs produce Polysucrose from 20 kDa to 1000 kDa. Polysucrose is provided as a dry powder and is extremely hydrophilic.

Can’t find what you are looking for? We can always produce a customised product for you. Read more here.

Structure
Polysucrose is a polymer synthesised by cross-linking sucrose with epichlorohydrin. Polysucrose has a more spherical structure and is less flexible compared to dextran.

Storage and stability
Polysucrose is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.

Solubility
Polysucrose dissolves readily in water.

Application
Polysucrose behaves as an ideal neutral sphere and it displays excellent biocompatibility. Read more about application here.

Other derivatives and polysaccharides

CM-polysucrose

Carboxymethyl-polysucrose (CM-polysucrose) consists of polysucrose (renamed from Ficoll™) substituted with carboxymethyl groups thereby imparting a polyanionic character to the product.

Read more

Other derivatives and polysaccharides

DEAE-polysucrose

DEAE-Polysucrose is a polysucrose (renamed from Ficoll™) substituted with diethylaminoethyl (DEAE) groups.

Read more

References

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How to order

Visit our webshop to see the molecular weights and pack sizes available. Please send an e-mail to order@tdblabs.se if you would like to receive a quote, place a bulk order or if you wish to place your order manually.

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