FITC-dextran sulfate

FITC-dextran sulfate

FITC-dextran sulfate is dextran sulfate sodium labeled with FITC, where the sulfur content is between 16 to 19%. All batches are checked for molecular weight, degree of substitution, sulfatation, loss on drying and free FITC. FITC-dextran sulfate is supplied as a yellow powder.

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Structure
Dextran is a branched polysaccharide elaborated by the bacteria Leuconostoc mesenteroides. Dextran is essentially a linear glucose chain linked by α-D-(1 – 6) linkages. The degree of branching is about 5 %. Dextran sulfate is manufactured by treating a selected dextran fraction with a sulfating agent (e.g. chlorosulfonic acid). The dextran sulfate is then labeled with FITC.

Spectral data
FITC-dextran sulfate has an excitation maximum of 490 – 495 nm and an emission maximum of 520 ± 5 nm.

Storage and stability
FITC-dextran sulfate is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.

Solubility
FITC-dextran sulfate dissolves readily in water.

 

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References

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  1. Danielsen, E. M. et al. Short-term tissue permeability actions of dextran sulfate sodium studied in a colon organ culture system. Tissue Barriers 0, 1728165 (2020).

Technical documents

How to order

Visit our webshop to see the molecular weights and pack sizes available. Please send an e-mail to order@tdblabs.se if you would like to receive a quote, place a bulk order or if you wish to place your order manually.

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